Research studies from all over the world have reported widespread, low-level contamination of the environment by cytostatic drugs in areas where the drugs are handled. It is evident that we are confronting a serious problem. Studies have found traces of cytostatic drugs on workbenches, floors, outer surfaces vials and exterior surfaces of safety cabinets and isolators. Contamination has even been found on the floor outside preparation rooms. Once contamination with cytostatic drugs has occurred, it is extremely difficult to eradicate.[1]
Cytostatic drugs are known to have mutagenic, carcinogenic and teratogenic effects. Occupational exposure to cytostatic drugs is a serious hazard for health care workers. Studies have also shown that occupational exposure is associated with increased frequency of miscarriage, infertility, birth defects, skin rashes and possibly leukaemia or other cancers. [2]
PhaSeal® is the only validated documented closed-system drugtransfer device on the market. Scientists across the world have tested the PhaSeal system by conducting highly-sensitive leak-tests under laboratory conditions. PhaSeal devices have also been evaluated in normal, day-to-day use in hospitals and clinics. These studies have shown that PhaSeal contains the drugs successfully and reduces the level of environmental contamination. [3]
